ALS (Amyotrophic Lateral Sclerosis), also known as Lou Gehrig's disease, is a cruel neurodegenerative disease with no cure. It leads to progressive paralysis and typically results in death within 3-5 years. Because ALS progression differs from patient to patient, it is very difficult to develop and test novel treatments.
The only way to measure ALS progression today is by using a questionnaire, called the ALS Functional Rating Scale-Revised (ALSFRS-R). But to participate in the questionnaire, patients have to reach a clinic with a trained ALS specialist and answer questions about their ability to speak, walk, breath, dress, and so on. This method has some serious limitations:
● It requires a visit to the clinic, which is costly and usually physically difficult, and therefore not readily adopted, leaving patients unmonitored.
● The questionnaire is highly subjective, both from the viewpoint of the interviewer (the clinician) and the interviewee (it might be the patient, a family member or professional caregiver), so the collected data are inconsistent, making the testing of ALS treatments very challenging.
● There is no single repository that stores the collected data.
Together, these and other factors are a major barrier today to finding a cure for ALS.
Your donation will support ongoing research and development on a groundbreaking application (app) that tracks the progression of ALS, offering new hope for patients of this devastating, fatal disease, for which there is no cure. The app, ALS Mobile Analyzer, developed by Prize4Life, has already won an important award, but further research and development will enhance its functions and improve the individual clinical care of ALS patients and clinical trials leading to discovery of a cure.